pathological effect of high concentration of oxygen in stones

Pathological Biomineralization of Kidney Stones

A dissolvable type of oxalate binds to calcium particles to form insoluble CaOx, which trigger the creation of reactive oxygen species (ROS), prompting renal endothelial damage and apoptosis (Khan...

Read More
Read More
(PDF) Effects of dissolved oxygen and fish size on Nile ...

2015-1-30  The present study was carried out to investigate effects of dissolved oxygen (DO) and fish size (FS) on growth, feed utilization, whole-body composition, and

Read More
Read More
Reactive Oxygen Species and the Hypomotility of the Gall ...

key pathological events in the formation of gallstones are the increase in the cholesterol:bile acid ratio, gall bladder hypo-motility, and an increase in the nucleating factors.

Read More
Read More
Pathological roles of reactive oxygen species and their ...

Reactive oxygen species generated by mitochondria, or from other sites within or outside the cell, cause damage to mitochondrial components and initiate degradative processes. Such toxic reactions...

Read More
Read More
[Affinity of oxygen for hemoglobin--its significance under ...

Hemoglobin-oxygen affinity attains pathological significance for oxygen supply during respiratory or metabolic alkalosis when the hemodynamic and tissue responses of the individual are limited: the increased affinity can critically lower capillary oxygen tension.

Read More
Read More
The impact of hyperoxia on brain activity: A resting-state ...

This study applied electroencephalography (EEG) in healthy subjects and investigated how high a concentration of oxygen in inhaled air (i.e., normobaric hyperoxia) alters brain activity under resting-state and task-evoked conditions.

Read More
Read More
Effect of pathological changes of pH, pO2 and pCO2 on the ...

Since standard susceptibility tests reflect the physiological rather than the pathological conditions prevailing within an infected abdomen, as recently documented, the effect of reduced pH and pO2 and increased pCO2 on the activity of antibiotics in vitro was studied.

Read More
Read More
Physiological and Pathological Responses to Hypoxia

Studies on isolated mitochondria have shown that the main effects of decreased oxygen availability on mitochondrial respiration is an inhibition of the respiratory chain and an increase of the proton leak, while phosphorylation is less affected. 12,13 The inhibition of the respiratory chain occurs at pO 2 levels high above the K m of cytochrome c oxidase, indicating that a specific inhibiting mechanism still unknown is switched on well before oxygen concentration

Read More
Read More
(PDF) Toxic Trace Metals and Pathological Changes in ...

containing a high concentration of Zn and Mn have been reported to cause anaemia, reduced bone formation, kidney stones and pneumonia (USDHH 2012, Y ogesh et al. 2013).

Read More
Read More
Negative Air Ions and Their Effects on Human Health and ...

2018-9-28  The removal efficiency under high concentration of NAIs reached about 50% after 15 min and almost 100% after 1.5 h. In a glass chamber (60 cm × 30 cm × 40 cm), 93% to 97% of the particles from fog or smoke was removed by NAIs within 6 min. Around 95%

Read More
Read More
Molecular modifiers reveal a mechanism of pathological ...

2016-8-8  The concentration of inhibitor in this study is approximately three orders of magnitude less than the concentration of Ca 2+ ions in supersaturated solution, indicating the effect of etch pit ...

Read More
Read More
Molecular modifiers reveal a mechanism of pathological ...

Like citrate, the molecule hydroxycitrate is shown to inhibit growth of the crystal that is the principal component of kidney stones, suggesting that hydroxycitrate could be another treatment for ...

Read More
Read More
Pathological and Therapeutic Significance of Cellular ...

Proteus mirabilis infection often leads to stone formation. We evaluated how bacterium-mucin adhesion, invasion, and intracellular crystal formation are related to antibiotic sensitivity and may cause frequent stone formation in enterocystoplasties. Five intestinal (Caco-2, HT29, HT29-18N2, HT29-FU, and HT29-MTX) and one ureter cell line (SV-HUC-1) were incubated in artificial urine with five ...

Read More
Read More
Research Advances in the Mechanisms of Hyperuricemia ...

Uric acid is the end product of purine metabolism in humans, and its excessive accumulation leads to hyperuricemia and urate crystal deposition in tissues including joints and kidneys. Hyperuricemia is considered an independent risk factor for cardiovascular and renal diseases. Although the symptoms of hyperuricemia-induced renal injury have long been known, the pathophysiological molecular ...

Read More
Read More
Toxicity, mechanism and health effects of some heavy ...

2014-6-1  The concentration of dissolved iron in the deep ocean is normally 0.6 nM or 33.5 × 10 −9 mg/L. In freshwater the concentration is very low with a detection level of 5 μg/L – ICP, whereas in groundwater the concentration of dissolved iron is very high with 20 mg/L (EPA, 1993).

Read More
Read More
Evaluation of antiurolithic effect and the possible ...

2011-8-6  Chinese herbs Desmodium styracifolium (Ds) and Pyrrosiae petiolosa (Pp) have been widely used to treat urolithiasis with few side effects in traditional Chinese medicine (TCM). In vitro crystallization study has confirmed their prophylaxis of Calcium oxalate (CaO x ) stones formation. However, little is known on their possible mechanisms in vivo. In the present study, we proposed to ...

Read More
Read More
Lactic acidosis: Symptoms, causes, and treatment

2018-2-9  The onset of lactic acidosis might be rapid and occur within minutes or hours, or gradual, happening over a period of days. The best way to treat lactic acidosis is to find out what has caused it.

Read More
Read More
Silica‐associated lung disease: An old‐world exposure in ...

2019-9-13  Understanding of high‐intensity short exposure is much less, although there appears to be a plume effect whereby short‐term high concentration exposure (>2 mg/m 3) has an effect three times as great as a cumulative equivalent longer term exposure at lower levels. 21

Read More
Read More
蚌埠医学院学报

2021-4-23  Abstract: ObjectiveTo investigate the expression of human microRNA let-7a1 and let-7c in lung cancer tissues and its relationship with clinicopathological features.MethodsThe surgical specimens and clinical data of 53 cases of lung tissue were collected, including 44 cases of lung cancer used to collect cancer tissue and paracancerous normal tissue, and 9 cases of benign lung disease tissue ...

Read More
Read More
Urobilinogen in Urine: Low High Levels + Normal Range ...

2021-4-7  Urobilinogen is a byproduct of bilirubin that is eventually eliminated through the stool and urine. Although urobilinogen is normally found in the urine, higher or lower levels may be a sign of a liver problem. Read on to find out what urobilinogen is, how it can be tested, and what its levels may reveal about your health.

Read More
Read More
(PDF) Pathological and Therapeutic Significance of ...

Pathological and Therapeutic Significance of Cellular Invasion by Proteus mirabilis in an Enterocystoplasty Infection Stone Model. Infection and Immunity, 2002. Rien Nijman. Download PDF. Download Full PDF Package. This paper. A short summary of this

Read More
Read More
Molecular modifiers reveal a mechanism of pathological ...

Like citrate, the molecule hydroxycitrate is shown to inhibit growth of the crystal that is the principal component of kidney stones, suggesting that hydroxycitrate could be another treatment for ...

Read More
Read More
The emerging role of reactive oxygen and nitrogen species ...

2012-6-13  (6) If concentration exceeds NO, peroxynitrate (O 2 NOO-) or nitrite form. (7) Excess over NO leads to the Fenton reaction, forming the rapidly reacting radical OH, associated with oxidative stress. (8) High CO 2 concentration (~1 mM) shifts decomposition of peroxynitrite towards forming NO 2. (b) Reactions forming , H 2 O 2 and OH.

Read More
Read More
Dietary Plants for the Prevention and Management of Kidney ...

2018-3-7  1. Introduction. Kidney stones, the formation of stones in the kidneys, is one of the oldest known and widespread diseases in the urinary tract system with a relapse rate of 50% in 5–10 years [1,2].It is the third most common disorder among urinary diseases [].It has been reported that 10–12% of people in industrialized countries (10% of men and 3% of women) have a urinary stone during ...

Read More
Read More
Research Advances in the Mechanisms of Hyperuricemia ...

Uric acid is the end product of purine metabolism in humans, and its excessive accumulation leads to hyperuricemia and urate crystal deposition in tissues including joints and kidneys. Hyperuricemia is considered an independent risk factor for cardiovascular and renal diseases. Although the symptoms of hyperuricemia-induced renal injury have long been known, the pathophysiological molecular ...

Read More
Read More
From crystalluria to kidney stones, some physicochemical ...

The effect of these two forces recently was studied in the context of high physiological crystal concentrations, renal tubular and pelvic dimensions and urinary transit times in the kidney. Crystals are even at the maximal concentration of 24000/cm 3 assumed in idiopathic Ca stone formers[ 9 ] on average in a distance of about 350 µ.

Read More
Read More
Toxicity, mechanism and health effects of some heavy ...

2014-6-1  The concentration of dissolved iron in the deep ocean is normally 0.6 nM or 33.5 × 10 −9 mg/L. In freshwater the concentration is very low with a detection level of 5 μg/L – ICP, whereas in groundwater the concentration of dissolved iron is very high with 20 mg/L (EPA, 1993).

Read More
Read More
Silica‐associated lung disease: An old‐world exposure in ...

2019-9-13  Understanding of high‐intensity short exposure is much less, although there appears to be a plume effect whereby short‐term high concentration exposure (>2 mg/m 3) has an effect three times as great as a cumulative equivalent longer term exposure at lower levels. 21

Read More
Read More
Hypoxia and hypoxia-inducible factors in chronic kidney ...

2016-7-6  The kidney is physiologically considered hypoxic despite receiving up to 20 % of the cardiac output in humans. Oxygen pressure in the renal cortex of normal animals is reportedly between 10 and 60 mmHg, whereas the corticomedullary junction and medulla are exposed to marked hypoxia [3–7].One critical cause of kidney hypoxia, particularly in the medulla, is the arterial–venous oxygen shunt ...

Read More
Read More
Urobilinogen in Urine: Low High Levels + Normal Range ...

2021-4-7  Urobilinogen is a byproduct of bilirubin that is eventually eliminated through the stool and urine. Although urobilinogen is normally found in the urine, higher or lower levels may be a sign of a liver problem. Read on to find out what urobilinogen is, how it can be tested, and what its levels may reveal about your health.

Read More
Read More